Background: | The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Applications: | WB, IHC |
Name of antibody: | TRIB3 |
Immunogen: | Fusion protein of human TRIB3 |
Full name: | tribbles pseudokinase 3 |
Synonyms: | NIPK; SINK; TRB3; SKIP3; C20orf97 |
SwissProt: | Q96RU7 |
IHC positive control: | human pancreas tissue and carcinoma of human pancreas tissue |
IHC Recommend dilution: | 30-150 |
WB Predicted band size: | 40 kDa |
WB Positive control: | HepG2 and SVT2 cell lysates |
WB Recommended dilution: | 200-1000 |