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技术规格
| Background: | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008] |
| Applications: | WB, IHC, IF |
| Name of antibody: | KRT19 |
| Immunogen: | Fusion protein of human KRT19 |
| Full name: | keratin 19 |
| Synonyms: | K19; CK19; K1CS |
| SwissProt: | P08727 |
| IHC positive control: | carcinoma of kidney tissue and adenocarcinoma of human ovary tissue; adenocarcinoma of endometrium tissue and carcinoma of human bladder tissue |
| IHC Recommend dilution: | 30-150 |
| WB Predicted band size: | 44 kDa |
| WB Positive control: | HepG2, HT-29, MDCK, PC12, MCF-7 cell lysates |
| WB Recommended dilution: | 500-2000 |
| IF Positive control: | COS7 cells transiently transfected by pCMV6-ENTRY |
| IF Recommended dilution: | 100-200 |
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